The Impact of Early Successful Primary Percutaneous Coronary Intervention on Left Ventricular Systolic Function in ST Elevation Myocardial Infarction Patients

Authors

  • Muhammad Rehanul Haq DHQ Hospital Khar Bajaur, Khyber Pakhtunkhwa -Pakistan.
  • Mujeebullah Tareen Bolan Medical College, Quetta -Pakistan.
  • Mukesh Kumar National Institute of Cardiovascular Diseases (NICVD), Karachi-Pakistan.
  • Abdul Hakeem National Institute of Cardiovascular Diseases (NICVD), Karachi-Pakistan.
  • Rajesh Kumar National Institute of Cardiovascular Diseases (NICVD), Karachi-Pakistan.
  • Jawaid Akbar Sial National Institute of Cardiovascular Diseases (NICVD), Karachi-Pakistan.
  • Tahir Saghir National Institute of Cardiovascular Diseases (NICVD), Karachi-Pakistan.
  • Syed Nadeem Hassan Rizvi National Institute of Cardiovascular Diseases (NICVD), Karachi-Pakistan.
  • Tariq Ashraf Karachi Institute of Heart Diseases, Karachi-Pakistan.

Keywords:

ST-Segment Elevation Myocardial Infarction, Primary Percutaneous Coronary Intervention, Left Ventricular Ejection Fraction, Thrombolysis

Abstract

Background: Treatment delay is considered to be one of the important predictors of survival in ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI). We investigated the impact of early successful PPCI for STEMI patients on left ventricular ejection fraction.

Methodology: This prospective study was carried out on 50 patients having STEMI undergoing PPCI in NICVD Karachi. Patients were divided into two groups, Group A, early presenter, patients received treatment with PPCI within six hours of the onset of symptoms, and group B, late presenter, patients received treatment after six hours up to twenty-four hours of the onset of symptoms.

Results: Group A patients showed promising results, having achieved TIMI grade III flow in 100%, whereas 85% of patients achieved TIMI grade III flow in group B (P = 0.02). There was a statistical difference between the two groups. Using Independent sample T-Test Group A patients showed improved LVEF as compared to Group B (at presentation 45.49±3.99% vs. 35.25±3.85%; P = 0.001 and at 3 months follow up 55.66±0.92% vs. 45.75±1.44%; P = 0.001).

Conclusion: Early PPCI treatment of STEMI patients can lead to improved TIMI grade flow and LVEF. Efforts must be made to shorten the delay in reperfusion therapy.

References

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Published

01-06-2022

How to Cite

Haq, M. R. ., Tareen, M. ., Kumar, M. ., Hakeem, A. ., Kumar, R. ., Sial, J. A. ., Saghir, T. ., Rizvi, S. N. H. ., & Ashraf, T. (2022). The Impact of Early Successful Primary Percutaneous Coronary Intervention on Left Ventricular Systolic Function in ST Elevation Myocardial Infarction Patients. Pakistan Journal of Cardiovascular Interventions, 2(1), 06–10. Retrieved from https://www.pjcvi.com/index.php/home/article/view/31

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